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Triterpenoid electrophiles (avicins) activate the innate stress response by redox regulation of a gene battery

Avicins are proapoptotic and anti-inflammatory triterpene electrophiles isolated from an Australian desert tree, Acacia victoriae. The presence of two α,β unsaturated carbonyl groups (Michael reaction sites) in the side chain of the avicin molecule prompted us to study its effects on NF-E2–related f...

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Detalhes bibliográficos
Main Authors: Haridas, Valsala, Hanausek, Margaret, Nishimura, Goshi, Soehnge, Holly, Gaikwad, Amos, Narog, Maciej, Spears, Erick, Zoltaszek, Robert, Walaszek, Zbigniew, Gutterman, Jordan U.
Formato: Artigo
Idioma:en
Publicado em: American Society for Clinical Investigation 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC300766/
https://ncbi.nlm.nih.gov/pubmed/14702110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200418699
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