Activation of the mitogen-activated protein kinase pathway in Triton X-100 disrupted NIH-3T3 cells by p21 ras and in vitro by plasma membranes from NIH 3T3 cells.

We describe a novel Triton-disrupted mammalian cell system wherein the pathways for activation of mitogen-activated protein (MAP) kinases (MAPKs) are capable of direct biochemical manipulation in vitro. MAPKs p42mapk and p44mapk are activated in signal transduction cascade(s) initiated by occupancy...

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Main Authors: Dent, P, Wu, J, Romero, G, Vincent, L A, Castle, D, Sturgill, T W
Formato: Artigo
Idioma:en
Publicado em: 1993
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC300952/
https://ncbi.nlm.nih.gov/pubmed/8334304
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https://ncbi.nlm.nih.gov/pmc/articles/PMC300952/
https://ncbi.nlm.nih.gov/pubmed/8334304

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