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Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30) complex

Saccharomyces cerevisiae SCF(Met30) ubiquitin–protein ligase controls cell cycle function and sulfur amino acid metabolism. We report here that the SCF(Met30) complex mediates the transcriptional repression of the MET gene network by triggering degradation of the transcriptional activator Met4p when...

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Main Authors:	Rouillon, Astrid, Barbey, Régine, Patton, E.Elizabeth, Tyers, Mike, Thomas, Dominique, Wang, Zuoren, Kiledjian, Megerditch, Copeland, Paul R., Fletcher, Julia E., Carlson, Bradley A., Hatfield, Dolph L., Driscoll, Donna M., Wang, Hongming, Boisvert, David, Kim, Kyeong Kyu, Kim, Rosalind, Kim, Sung-Hou, Kushnirov, Vitaly V., Kochneva-Pervukhova, Natalia V., Chechenova, Maria B., Frolova, Natalia S., Ter–Avanesyan, Michael D., Schmitt, Nicole, Schwarz, Martin, Peretz, Asher, Abitbol, Ilane, Attali, Bernard, Pongs, Olaf, Hisahara, Shin, Araki, Takashi, Sugiyama, Fumihiro, Yagami, Ken–ichi, Suzuki, Misao, Abe, Kuniya, Yamamura, Ken–ichi, Miyazaki, Jun–ichi, Momoi, Takashi, Saruta, Takao, Bernard, Claude C.A., Okano, Hideyuki, Miura, Masayuki, Xing, Heming, Zhang, Shaosong, Weinheimer, Carla, Kovacs, Attila, Muslin, Anthony J., Müller, Judith M., Isele, Ulrike, Metzger, Eric, Rempel, Annette, Moser, Markus, Pscherer, Armin, Breyer, Tobias, Holubarsch, Christian, Buettner, Reinhard, Schüle, Roland, Nikolova, Penka V., Wong, Kam-Bo, DeDecker, Brian, Henckel, Julia, Fersht, Alan R., de la Barre, Anne-Elisabeth, Gerson, Véronique, Gout, Stéphanie, Creaven, Martina, Allis, C.Dave, Dimitrov, Stefan, Wang, Demin, Moriggl, Richard, Stravopodis, Dimitrios, Carpino, Nick, Marine, Jean–Christophe, Teglund, Stephan, Feng, Jian, Ihle, James N., Ducker, Charles E., Simpson, Robert T., Sträßer, Katja, Hurt, Ed, Schramm, Carolin, Elliott, Sarah, Shevchenko, Anna, Shevchenko, Andrej, Schiebel, Elmar, Raught, Brian, Gingras, Anne-Claude, Gygi, Steven P., Imataka, Hiroaki, Morino, Shigenobu, Gradi, Alessandra, Aebersold, Ruedi, Sonenberg, Nahum, Cahuzac, Bertrand, Berthonneau, Eric, Birlirakis, Nicolas, Guittet, Eric, Mirande, Marc, Kuroda, Masahiko, Sok, John, Webb, Lisa, Baechtold, Heidi, Urano, Fumihiko, Yin, Yin, Chung, Peter, de Rooij, Dirk G., Akhmedov, Alexandre, Ashley, Terry, Ron, David, Morrison, Ciaran, Sonoda, Eiichiro, Takao, Noriaki, Shinohara, Akira, Yamamoto, Ken-ichi, Takeda, Shunichi, Herrera, Eloísa, Martínez-A, Carlos, Blasco, María A., Zolnierowicz, Stanislaw, Bollen, Mathieu, Nissen, Poul, Kjeldgaard, Morten, Nyborg, Jens, Parekh, Davey B., Ziegler, Wolfgang, Parker, Peter J., Grishkovskaya, Irina, Avvakumov, George V., Sklenar, Gisela, Dales, David, Hammond, Geoffrey L., Muller, Yves A., Batista, Facundo D., Neuberger, Michael S., Masuda, Minako, Betancourt, Lazaro, Matsuzawa, Takeshi, Kashimoto, Takashige, Takao, Toshifumi, Shimonishi, Yasutsugu, Horiguchi, Yasuhiko, de Leeuw, E., te Kaat, K., Moser, C., Menestrina, G., Demel, R., de Kruijff, B., Oudega, B., Luirink, J., Sinning, I., Scotti, Pier A., Urbanus, Malene L., Brunner, Josef, de Gier, Jan-Willem L., von Heijne, Gunnar, van der Does, Chris, Driessen, Arnold J.M., Oudega, Bauke, Luirink, Joen, Hill, Kathryn, Cooper, Antony A., Ito, Akihiko, Kataoka, Tatsuki R., Watanabe, Masafumi, Nishiyama, Kazutaka, Mazaki, Yuichi, Sabe, Hisataka, Kitamura, Yukihiko, Nojima, Hiroshi, Steinmetz, Michel O., Kammerer, Richard A., Jahnke, Wolfgang, Goldie, Kenneth N., Lustig, Ariel, van Oostrum, Jan, Vallée, François, Lipari, Francesco, Yip, Patrick, Sleno, Barry, Herscovics, Annette, Howell, P.Lynne, Goyal, Lakshmi, McCall, Kimberly, Agapite, Julie, Hartwieg, Erika, Steller, Hermann, Meier, Pascal, Silke, John, Leevers, Sally J., Evan, Gerard I., Smith-Hicks, Constance L., Sizer, Kurt C., Powers, James F., Tischler, Arthur S., Costantini, Frank, Goi, Takanori, Shipitsin, Michail, Lu, Zhimin, Foster, David A., Klinz, Stephan G., Feig, Larry A., Welch, Martin, Todd, Daniel E., Whitehead, Neil A., McGowan, Simon J., Bycroft, Barrie W., Salmond, George P.C., Qian, Xiaolan, Esteban, Luis, Vass, William C., Upadhyaya, Cheerag, Papageorge, Alex G., Yienger, Kate, Ward, Jerrold M., Lowy, Douglas R., Santos, Eugenio, Bouwman, Peter, Göllner, Heike, Elsässer, Hans-Peter, Eckhoff, Gabriele, Karis, Alar, Grosveld, Frank, Philipsen, Sjaak, Suske, Guntram, Martínez-Balbás, Marian A., Bauer, Uta-Maria, Nielsen, Søren J., Brehm, Alexander, Kouzarides, Tony, Xie, Jun, Collart, Martine, Lemaire, Marc, Stelzer, Gertraud, Meisterernst, Michael, Vogel, Jodi L., Kristie, Thomas M., Kane, Christopher D., Means, Anthony R., Brassinga, Ann Karen C., Gorbatyuk, Boris, Ouimet, Marie–Claude, Marczynski, Gregory T., Lewis, Peter J., Thaker, Shail D., Errington, Jeffrey, Espeso, Eduardo A., Roncal, Tomás, Díez, Eliecer, Rainbow, Lynne, Bignell, Elaine, Álvaro, Josué, Suárez, Teresa, Denison, Steven H., Tilburn, Joan, Arst, Herbert N., Peñalva, Miguel A., Jin, Dong-Yan, Wang, Hai-Lin, Zhou, Yuan, Chun, Abel C.S., Kibler, Karen V., Hou, Yun-De, Kung, Hsiang-fu, Jeang, Kuan-Teh
Formato:	Artigo
Idioma:	English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English
Publicado em:	Oxford University Press 2000
Assuntos:	Articles Corrigenda EMBO Conference Report Reviews
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Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30) complex

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