Male sterility and enhanced radiation sensitivity in TLS(–/–) mice

TLS (also known as FUS) is an RNA-binding protein that contributes the N-terminal half of fusion oncoproteins implicated in the development of human liposarcomas and leukemias. Here we report that male mice homozygous for an induced mutation in TLS are sterile with a marked increase in the number of...

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Main Authors: Kuroda, Masahiko, Sok, John, Webb, Lisa, Baechtold, Heidi, Urano, Fumihiko, Yin, Yin, Chung, Peter, de Rooij, Dirk G., Akhmedov, Alexandre, Ashley, Terry, Ron, David
Formato: Artigo
Idioma:en
Publicado em: Oxford University Press 2000
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC305582/
https://ncbi.nlm.nih.gov/pubmed/10654943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.3.453
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https://ncbi.nlm.nih.gov/pmc/articles/PMC305582/
https://ncbi.nlm.nih.gov/pubmed/10654943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.3.453

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