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Using three-dimensional microfluidic networks for solving computationally hard problems

This paper describes the design of a parallel algorithm that uses moving fluids in a three-dimensional microfluidic system to solve a nondeterministically polynomial complete problem (the maximal clique problem) in polynomial time. This algorithm relies on (i) parallel fabrication of the microfluidi...

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Main Authors:	Chiu, Daniel T., Pezzoli, Elena, Wu, Hongkai, Stroock, Abraham D., Whitesides, George M., Nazif, Tamim, Bogyo, Matthew, Remacle, F., Schlag, E. W., Selzle, H., Kompa, K. L., Even, U., Levine, R. D., Niewoehner, Wesley A., Alonso, Darwin O. V., DeArmond, Stephen J., Cohen, Fred E., Daggett, Valerie, Elcock, Adrian H., McCammon, J. Andrew, Crosson, Sean, Moffat, Keith, Dang, Pham My-Chan, Cross, Andrew R., Babior, Bernard M., Altose, Michael D., Zheng, Yuangang, Dong, Jian, Palfey, Bruce A., Carey, Paul R., Petros, Andrew M., Medek, Ales, Nettesheim, David G., Kim, Daniel H., Yoon, Ho Sup, Swift, Kerry, Matayoshi, Edmund D., Oltersdorf, Tilman, Fesik, Stephen W., Kang, Hong-Yo, Lin, Hui-Kuan, Hu, Yueh-Chiang, Yeh, Shuyuan, Huang, Ko-En, Chang, Chawnshang, He, Xiaodun, Lehman, I. R., Murer, Valérie, Spetz, Jean François, Hengst, Ulrich, Altrogge, Ludger Maria, de Agostini, Ariane, Monard, Denis, DaFonseca, Christopher J., Shu, Fong, Zhang, J. Jillian, Karzai, A. Wali, Sauer, Robert T., Vologodskii, Alexander V., Zhang, Wentao, Rybenkov, Valentin V., Podtelezhnikov, Alexei A., Subramanian, Deepa, Griffith, Jack D., Cozzarelli, Nicholas R., Ho, C. Kiong, Shuman, Stewart, Xie, Youming, Varshavsky, Alexander, Mergny, Jean-Louis, Lacroix, Laurent, Teulade-Fichou, Marie-Paule, Hounsou, Candide, Guittat, Lionel, Hoarau, Magali, Arimondo, Paola B., Vigneron, Jean-Pierre, Lehn, Jean-Marie, Riou, Jean-François, Garestier, Thérèse, Hélène, Claude, Podust, Larissa M., Poulos, Thomas L., Waterman, Michael R., Zuccheri, Giampaolo, Scipioni, Anita, Cavaliere, Valeria, Gargiulo, Giuseppe, De Santis, Pasquale, Samorì, Bruno, Watanabe, Takuo, Huang, Hsien-Bin, Horiuchi, Atsuko, da Cruze Silva, Edgar F., Hsieh-Wilson, Linda, Allen, Patrick B., Shenolikar, Shirish, Greengard, Paul, Nairn, Angus C., Adelman, Karen, Salmon, Brandy, Baines, Joel D., Silverman, J. A., Balakrishnan, R., Harbury, P. B., Török, Zsolt, Goloubinoff, Pierre, Horváth, Ibolya, Tsvetkova, Nelly M., Glatz, Attila, Balogh, Gábor, Varvasovszki, Viktória, Los, Dmitry A., Vierling, Elizabeth, Crowe, John H., Vígh, László, Chirala, Subrahmanyam S., Jayakumar, Armugam, Gu, Zi-Wei, Wakil, Salih J., Nohaile, M. J., Hendsch, Z. S., Tidor, B., Sauer, R. T., Kamada, Katsuhiko, De Angelis, Jacqueline, Roeder, Robert G., Burley, Stephen K., Heikinheimo, P., Tuominen, V., Ahonen, A.-K., Teplyakov, A., Cooperman, B. S., Baykov, A. A., Lahti, R., Goldman, A., Brown, C. Kent, Madauss, Kevin, Lian, Wei, Beck, Moriah R., Tolbert, W. David, Rodgers, David W., Ellgaard, Lars, Riek, Roland, Herrmann, Torsten, Güntert, Peter, Braun, Daniel, Helenius, Ari, Wüthrich, Kurt, Sinha, Neeti, Nussinov, Ruth, Petty, Howard R., Kindzelskii, Andrei L., Rivas, Germán, Fernández, Javier A., Minton, Allen P., Pellegrini, Graziella, Dellambra, Elena, Golisano, Osvaldo, Martinelli, Enrica, Fantozzi, Ivana, Bondanza, Sergio, Ponzin, Diego, McKeon, Frank, De Luca, Michele, Boldogh, Istvan R., Yang, Hyeong-Cheol, Nowakowski, W. Dan, Karmon, Sharon L., Hays, Lara G., Yates, John R., Pon, Liza A., Zhang, Zongming, Tang, Jisen, Tikunova, Svetlana, Johnson, J. David, Chen, Zhangguo, Qin, Ning, Dietrich, Alexander, Stefani, Enrico, Birnbaumer, Lutz, Zhu, Michael Xi, Cohen, Haim, Sinclair, David A., Lafont, Frank, Simons, Kai, Walev, Iwan, Bhakdi, Sebastian Chakrit, Hofmann, Fred, Djonder, Nabil, Valeva, Angela, Aktories, Klaus, Bhakdi, Sucharit, Wu, Xiaosheng, Kasper, Lawryn H., Mantcheva, Ralitsa T., Mantchev, George T., Springett, Margaret J., van Deursen, Jan M. A., Nagai, Takeharu, Sawano, Asako, Park, Eun Sun, Miyawaki, Atsushi, Liu, Bin, Gross, Mitchell, ten Hoeve, Johanna, Shuai, Ke, Fontoura, Beatriz M. A., Dales, Samuel, Blobel, Günter, Zhong, Hualin, Stephen, Antonia E., Masiakos, Peter T., Segev, Dorry L., Vacanti, Joseph P., Donahoe, Patricia K., MacLaughlin, David T., Wang, Lin, Sunahara, Roger K., Krumins, Andrejs, Perkins, Guy, Crochiere, Marsha L., Mackey, Mason, Bell, Sean, Ellisman, Mark H., Taylor, Susan S., Moore, Gregory L., Maranas, Costas D., Lutz, Stefan, Benkovic, Stephen J., Levy-Lahad, E., Lahad, A., Eisenberg, S., Dagan, E., Paperna, T., Kasinetz, L., Catane, R., Kaufman, B., Beller, U., Renbaum, P., Gershoni-Baruch, R., Oliveira, Sofia A., Shenk, Thomas E., Sekiguchi, JoAnn, Ferguson, David O., Chen, Hua Tang, Yang, Eva Mary, Earle, John, Frank, Karen, Whitlow, Scott, Gu, Yansong, Xu, Yang, Nussenzweig, André, Alt, Frederick W.
Formato:	Artigo
Idioma:	English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English
Publicado em:	The National Academy of Sciences 2001
Assuntos:	Physical Sciences Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.gov/pmc/articles/PMC30589/ https://ncbi.nlm.nih.gov/pubmed/11248014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061014198 https://ncbi.nlm.nih.gov/pmc/articles/PMC30590/ https://ncbi.nlm.nih.gov/pubmed/11248015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061028898 https://ncbi.nlm.nih.gov/pmc/articles/PMC30591/ https://ncbi.nlm.nih.gov/pubmed/11248016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061019998 https://ncbi.nlm.nih.gov/pmc/articles/PMC30592/ https://ncbi.nlm.nih.gov/pubmed/11248017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.041588898 https://ncbi.nlm.nih.gov/pmc/articles/PMC30593/ https://ncbi.nlm.nih.gov/pubmed/11248018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061555898 https://ncbi.nlm.nih.gov/pmc/articles/PMC30594/ https://ncbi.nlm.nih.gov/pubmed/11248019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061411798 https://ncbi.nlm.nih.gov/pmc/articles/PMC30595/ 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Using three-dimensional microfluidic networks for solving computationally hard problems

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