Single point mutations affect fatty acid block of human myocardial sodium channel α subunit Na(+) channels

Suppression of cardiac voltage-gated Na(+) currents is probably one of the important factors for the cardioprotective effects of the n-3 polyunsaturated fatty acids (PUFAs) against lethal arrhythmias. The α subunit of the human cardiac Na(+) channel (hH1(α)) and its mutants were expressed in human e...

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Detalhes bibliográficos
Main Authors: Xiao, Yong-Fu, Ke, Qingen, Wang, Sho-Ya, Auktor, Klaus, Yang, Yinke, Wang, Ging Kuo, Morgan, James P., Leaf, Alexander
Formato: Artigo
Idioma:en
Publicado em: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC30700/
https://ncbi.nlm.nih.gov/pubmed/11248125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061003798
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https://ncbi.nlm.nih.gov/pmc/articles/PMC30700/
https://ncbi.nlm.nih.gov/pubmed/11248125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061003798

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