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Intracellular bacteria recognition contributes to maximal interleukin (IL)-12 production by IL-10-deficient macrophages
Interleukin (IL)-12 is a key factor that induces T helper cell type 1-mediated immunity and inflammatory diseases. In some colitis models, such as IL-10 knock-out (KO) mice, IL-12 triggers intestinal inflammation. An abundant amount of IL-12 is produced by intestinal macrophages in response to stimu...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
Blackwell Science Inc
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3074226/ https://ncbi.nlm.nih.gov/pubmed/21352199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2011.04318.x |
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