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The Drosophila homolog of Down's syndrome critical region 1 gene regulates learning: Implications for mental retardation

Mental retardation is the most common phenotypic abnormality seen in Down's syndrome (DS) patients, yet the underlying mechanism remains mysterious. DS critical region 1 (DSCR1), located on chromosome 21, is overexpressed in the brain of DS fetus and encodes an inhibitor of calcineurin, but its...

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Detalhes bibliográficos
Main Authors: Chang, Karen T., Shi, Yi-Jun, Min, Kyung-Tai
Formato: Artigo
Idioma:en
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC307647/
https://ncbi.nlm.nih.gov/pubmed/14668437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2536696100
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