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Improved DNA Sequencing Accuracy and Detection of Heterozygous Alleles Using Manganese Citrate and Different Fluorescent Dye Terminators

The use of dideoxynucleotide triphosphates labeled with different fluorescent dyes (dye terminators) is the most versatile method for automated DNA sequencing. However, variation in peak heights reduces base-calling accuracy and limits heterozygous allele detection, favoring use of dye-labeled prime...

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Detalhes bibliográficos
Main Authors:	Korch, Christopher, Drabkin, Harry, Korenberg, Julie R., Chen, Xiao-Ning, Devon, Keri L., Noya, David, Oster-Granite, Mary L., Birren, Bruce W., Lindgren, Gabriella, Sandberg, Kaj, Persson, Helena, Marklund, Stefan, Breen, Matthew, Sandgren, Björn, Carlstén, Johan, Ellegren, Hans, Ellsworth, Rachel E., Ionasescu, Victor, Searby, Charles, Sheffield, Val C., Braden, Valerie V., Kucaba, Tamara A., McPherson, John D., Marra, Marco A., Green, Eric D., Florea, Liliana, Hartzell, George, Zhang, Zheng, Rubin, Gerald M., Miller, Webb, Cabin, Deborah E., McKee-Johnson, Jennifer W., Matesic, Lydia E., Wiltshire, Tim, Rue, Elizabeth E., Mjaatvedt, Anne E., Huo, Yong Kang, Reeves, Roger H., Hammell, Amy B., Taylor, Ronald C., Peltz, Stuart W., Dinman, Jonathan D., Winick, Jeffrey D., Friedman, Jeffrey M., Brunner, Bodo, Todt, Tilman, Lenzner, Steffen, Stout, Karen, Schulz, Ute, Ropers, Hans-Hilger, Kalscheuer, Vera M., Wendl, Michael C., Dear, Simon, Hodgson, Dave, Hillier, LaDeana, DeSilva, Udaya, Massa, Hillary, Trask, Barbara J., Gururajan, Rajagopal, Lahti, Jill M., Grenet, Jose, Easton, John, Gruber, Irmhild, Ambros, Peter F., Kidd, Vincent J., Mackiewicz, Pawel, Gierlik, Agnieszka, Kowalczuk, Maria, Dudek, Miroslaw R., Cebrat, Stanislaw, Deere, Michelle, Dieguez, Jose L., Yoon, Sung-Joo Kim, Hewett-Emmett, David, de la Chapelle, Albert, Hecht, Jacqueline T., Taillon-Miller, Patricia, Piernot, Ellen E., Kwok, Pui-Yan, Itoh, Masayoshi, Kitsunai, Tokuji, Akiyama, Junichi, Shibata, Kazuhiro, Izawa, Masaki, Kawai, Jun, Tomaru, Yasuhiro, Carninci, Piero, Shibata, Yuko, Ozawa, Yasuhiro, Muramatsu, Masami, Okazaki, Yasushi, Hayashizaki, Yoshihide, Welle, Stephen, Bhatt, Kirti, Thornton, Charles A., Bouck, John, Gorrell, James H., Muzny, Donna, Gibbs, Richard A., Glöckner, Gernot, Scherer, Stephen, Schattevoy, Ruben, Boright, Andrew, Weber, Jacqueline, Tsui, Lap-Chee, Rosenthal, André, Zander, Cecilia, Thelaus, Jonas, Lindblad, Kerstin, Karlsson, Mikael, Sjöberg, Kjell, Schalling, Martin, Brāzma, Alvis, Jonassen, Inge, Vilo, Jaak, Ukkonen, Esko, Centola, Michael, Chen, Xiaoguang, Sood, Raman, Deng, Zuoming, Aksentijevich, Ivona, Blake, Trevor, Ricke, Darrell O., Chen, Xiang, Wood, Geryl, Zaks, Nurit, Richards, Neil, Krizman, David, Mansfield, Elizabeth, Apostolou, Sinoula, Liu, Jingmei, Shafran, Neta, Vedula, Anil, Hamon, Melanie, Cercek, Andrea, Kahan, Tanaz, Gumucio, Deborah, Callen, David F., Richards, Robert I., Moyzis, Robert K., Doggett, Norman A., Collins, Francis S., Liu, P. Paul, Fischel-Ghodsian, Nathan, Kastner, Daniel L., Paternotte, Caroline, Rudnicki, Doda, Fizames, Cécile, Davoine, Claire-Sophie, Mavel, Delphine, Dürr, Alexandra, Samson, Delphine, Marquette, Catherine, Muselet, Delphine, Vega-Czarny, Nathalie, Drouot, Nathalie, Voit, Thomas, Fontaine, Bertrand, Gyapay, Gabor, Auburger, Georg, Weissenbach, Jean, Hazan, Jamilé, Pilgrim, Dave, Murty, Vundavalli V.V.S., Montgomery, Kate, Dutta, Shipra, Bala, Shashi, Renault, Beatrice, Bosl, George J., Kucherlapati, Raju, Chaganti, Raju S.K., Maercker, Christian, Kortwig, Heike, Lipps, Hans J., Giraudeau, Fabienne, Petit, Elisabeth, Avet-Loiseau, Hervé, Hauck, Yolande, Vergnaud, Gilles, Amarger, Valérie, Manenti, Giacomo, Stafford, Amanda, De Gregorio, Laura, Gariboldi, Manuela, Falvella, F. Stefania, Avner, Philip, Dragani, Tommaso A., Cao, Yicheng, Kang, Hyung Lyun, Xu, Xuequn, Wang, Mei, Dho, So Hee, Huh, Jun Ryul, Lee, Byeong-Jae, Kalush, Francis, Bocskai, Diana, Ding, Yan, Tesmer, Judith G., Lee, Jonghyeob, Moon, Eunpyo, Jurecic, Vesna, Baldini, Antonio, Weier, Heinz-Ulrich, Simon, Melvin I., Adams, Mark D., Kim, Ung-Jin, Steingruber, Helen E., Dunham, Andrew, Coffey, Alison J., Clegg, Sheila M., Howell, Gareth R., Maslen, Gareth L., Scott, Carol E., Gwilliam, Rhian, Hunt, Paul J., Sotheran, Elizabeth C., Huckle, Elizabeth J., Hunt, Sarah E., Dhami, Pawandeep, Soderlund, Cari, Leversha, Margaret A., Bentley, David R., Ross, Mark T., Long, Anthony D., Langley, Charles H., Lengeling, Andreas, Otmani, Chris, Bućan, Maja, Piper, Michael B., Bankier, Alan T., Dear, Paul H., Stein, Lincoln D., Thierry-Mieg, Jean, Wolfsberg, Tyra G., Gabrielian, Andrei E., Campbell, Michael J., Cho, Raymond J., Spouge, John L., Landsman, David, Alonso, Santos, Armour, John A.L., Zhu, Heng, Blackmon, Barbara P., Sasinowski, Maciek, Dean, Ralph A., Peterson, Raymond J., Goldman, David, Long, Jeffrey C., Bull, Laura N., Pabón-Peña, Carlos R., Freimer, Nelson B., Reiter, Lawrence T., Liehr, Thomas, Rautenstrauss, Bernd, Robertson, Hugh M., Lupski, James R., Schmalzing, Dieter, Tsao, Norman, Koutny, Lance, Chisholm, Dan, Srivastava, Alok, Adourian, Aram, Linton, Lauren, McEwan, Paul, Matsudaira, Paul, Ehrlich, Daniel, Schalkwyk, Leonard C., Jung, Martin, Daser, Angelika, Weiher, Michael, Walter, Jörn, Himmelbauer, Heinz, Lehrach, Hans, Huang, Xiaoqiu, Madan, Anup, Liu, Leo X., Spoerke, Jill M., Mulligan, Evan L., Chen, Jing, Reardon, Brian, Westlund, Bethany, Sun, Lin, Abel, Ken, Armstrong, Barbara, Hardiman, Gary, King, Judith, McCague, Lisa, Basson, Michael, Clover, Ralph, Johnson, Carl D., Devos, Katrien M., Beales, James, Nagamura, Yoshiaki, Sasaki, Takuji, Lese, Christa M., Fantes, Judy A., Riethman, Harold C., Ledbetter, David H., Jareborg, Niclas, Birney, Ewan, Durbin, Richard, Hegele, Robert A., Anderson, Carol, Young, T. Kue, Connelly, Philip W., White, Peter S., Sulman, Erik P., Porter, Christopher J., Matise, Tara C., Pálsson, Birgir, Pálsson, Frosti, Perlin, Mark, Gudbjartsson, Hákon, Stefánsson, Kári, Gulcher , Jeffrey
Formato:	Artigo
Idioma:	English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English
Publicado em:	Cold Spring Harbor Laboratory Press 1999
Assuntos:	Methods Resource Letter Genome Methods
Acesso em linha:	https://ncbi.nlm.nih.gov/pmc/articles/PMC310770/ https://ncbi.nlm.nih.gov/pubmed/10400927 https://ncbi.nlm.nih.gov/pmc/articles/PMC310771/ https://ncbi.nlm.nih.gov/pubmed/10330132 https://ncbi.nlm.nih.gov/pmc/articles/PMC310772/ https://ncbi.nlm.nih.gov/pubmed/9750194 https://ncbi.nlm.nih.gov/pmc/articles/PMC310773/ https://ncbi.nlm.nih.gov/pubmed/10400924 https://ncbi.nlm.nih.gov/pmc/articles/PMC310774/ https://ncbi.nlm.nih.gov/pubmed/9750195 https://ncbi.nlm.nih.gov/pmc/articles/PMC310775/ https://ncbi.nlm.nih.gov/pubmed/9750193 https://ncbi.nlm.nih.gov/pmc/articles/PMC310776/ https://ncbi.nlm.nih.gov/pubmed/10330121 https://ncbi.nlm.nih.gov/pmc/articles/PMC310777/ https://ncbi.nlm.nih.gov/pubmed/9750197 https://ncbi.nlm.nih.gov/pmc/articles/PMC310778/ https://ncbi.nlm.nih.gov/pubmed/10330123 https://ncbi.nlm.nih.gov/pmc/articles/PMC310779/ https://ncbi.nlm.nih.gov/pubmed/9750196 https://ncbi.nlm.nih.gov/pmc/articles/PMC310780/ https://ncbi.nlm.nih.gov/pubmed/10330122 https://ncbi.nlm.nih.gov/pmc/articles/PMC310781/ https://ncbi.nlm.nih.gov/pubmed/9750192 https://ncbi.nlm.nih.gov/pmc/articles/PMC310782/ https://ncbi.nlm.nih.gov/pubmed/10330120 https://ncbi.nlm.nih.gov/pmc/articles/PMC310783/ https://ncbi.nlm.nih.gov/pubmed/10330124 https://ncbi.nlm.nih.gov/pmc/articles/PMC310784/ https://ncbi.nlm.nih.gov/pubmed/10330130 https://ncbi.nlm.nih.gov/pmc/articles/PMC310785/ https://ncbi.nlm.nih.gov/pubmed/10330126 https://ncbi.nlm.nih.gov/pmc/articles/PMC310786/ https://ncbi.nlm.nih.gov/pubmed/10330131 https://ncbi.nlm.nih.gov/pmc/articles/PMC310787/ https://ncbi.nlm.nih.gov/pubmed/9799794 https://ncbi.nlm.nih.gov/pmc/articles/PMC310788/ https://ncbi.nlm.nih.gov/pubmed/9799793 https://ncbi.nlm.nih.gov/pmc/articles/PMC310789/ https://ncbi.nlm.nih.gov/pubmed/9799795 https://ncbi.nlm.nih.gov/pmc/articles/PMC310790/ https://ncbi.nlm.nih.gov/pubmed/9847082 https://ncbi.nlm.nih.gov/pmc/articles/PMC310791/ https://ncbi.nlm.nih.gov/pubmed/9847080 https://ncbi.nlm.nih.gov/pmc/articles/PMC310792/ https://ncbi.nlm.nih.gov/pubmed/9847083 https://ncbi.nlm.nih.gov/pmc/articles/PMC310793/ https://ncbi.nlm.nih.gov/pubmed/9847081 https://ncbi.nlm.nih.gov/pmc/articles/PMC310794/ https://ncbi.nlm.nih.gov/pubmed/10413405 https://ncbi.nlm.nih.gov/pmc/articles/PMC310795/ https://ncbi.nlm.nih.gov/pubmed/10413404 https://ncbi.nlm.nih.gov/pmc/articles/PMC310796/ https://ncbi.nlm.nih.gov/pubmed/10413403 https://ncbi.nlm.nih.gov/pmc/articles/PMC310797/ https://ncbi.nlm.nih.gov/pubmed/10413402 https://ncbi.nlm.nih.gov/pmc/articles/PMC310798/ https://ncbi.nlm.nih.gov/pubmed/10447511 https://ncbi.nlm.nih.gov/pmc/articles/PMC310799/ https://ncbi.nlm.nih.gov/pubmed/10447510 https://ncbi.nlm.nih.gov/pmc/articles/PMC310800/ https://ncbi.nlm.nih.gov/pubmed/10447507 https://ncbi.nlm.nih.gov/pmc/articles/PMC310801/ https://ncbi.nlm.nih.gov/pubmed/10447508 https://ncbi.nlm.nih.gov/pmc/articles/PMC310802/ https://ncbi.nlm.nih.gov/pubmed/9872984 https://ncbi.nlm.nih.gov/pmc/articles/PMC310803/ https://ncbi.nlm.nih.gov/pubmed/9872985 https://ncbi.nlm.nih.gov/pmc/articles/PMC310804/ https://ncbi.nlm.nih.gov/pubmed/10447512 https://ncbi.nlm.nih.gov/pmc/articles/PMC310805/ https://ncbi.nlm.nih.gov/pubmed/9872983 https://ncbi.nlm.nih.gov/pmc/articles/PMC310806/ https://ncbi.nlm.nih.gov/pubmed/10447509 https://ncbi.nlm.nih.gov/pmc/articles/PMC310807/ https://ncbi.nlm.nih.gov/pubmed/10508843 https://ncbi.nlm.nih.gov/pmc/articles/PMC310808/ https://ncbi.nlm.nih.gov/pubmed/10508841 https://ncbi.nlm.nih.gov/pmc/articles/PMC310809/ https://ncbi.nlm.nih.gov/pubmed/10508842 https://ncbi.nlm.nih.gov/pmc/articles/PMC310810/ https://ncbi.nlm.nih.gov/pubmed/10508844 https://ncbi.nlm.nih.gov/pmc/articles/PMC310811/ https://ncbi.nlm.nih.gov/pubmed/10508847 https://ncbi.nlm.nih.gov/pmc/articles/PMC310812/ https://ncbi.nlm.nih.gov/pubmed/10508846 https://ncbi.nlm.nih.gov/pmc/articles/PMC310813/ https://ncbi.nlm.nih.gov/pubmed/10508845 https://ncbi.nlm.nih.gov/pmc/articles/PMC310814/ https://ncbi.nlm.nih.gov/pubmed/10508840 https://ncbi.nlm.nih.gov/pmc/articles/PMC310815/ https://ncbi.nlm.nih.gov/pubmed/10508848 https://ncbi.nlm.nih.gov/pmc/articles/PMC310816/ https://ncbi.nlm.nih.gov/pubmed/10508839 https://ncbi.nlm.nih.gov/pmc/articles/PMC310817/ https://ncbi.nlm.nih.gov/pubmed/10523525 https://ncbi.nlm.nih.gov/pmc/articles/PMC310818/ https://ncbi.nlm.nih.gov/pubmed/10523526 https://ncbi.nlm.nih.gov/pmc/articles/PMC310819/ https://ncbi.nlm.nih.gov/pubmed/10523529
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Improved DNA Sequencing Accuracy and Detection of Heterozygous Alleles Using Manganese Citrate and Different Fluorescent Dye Terminators

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