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2D NMR-spectroscopic screening reveals polyketides in ladybugs

Small molecules of biological origin continue to yield the most promising leads for drug design, but systematic approaches for exploring nature’s cache of structural diversity are lacking. Here, we demonstrate the use of 2D NMR spectroscopy to screen a library of biorationally selected insect metabo...

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Detalhes bibliográficos
Formato: Artigo
Idioma:en
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116430/
https://ncbi.nlm.nih.gov/pubmed/21646540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107020108
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