Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia

Low folate intake as well as alterations in folate metabolism as a result of polymorphisms in the enzyme methylenetetrahydrofolate reductase (MTHFR) have been associated with an increased incidence of neural tube defects, vascular disease, and some cancers. Polymorphic variants of MTHFR lead to enha...

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Detalhes bibliográficos
Main Authors: Wiemels, Joseph L., Smith, Rosalyn N., Taylor, G. Malcolm, Eden, Osborn B., Alexander, Freda E., Greaves, Mel F.
Formato: Artigo
Idioma:en
Publicado em: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC31169/
https://ncbi.nlm.nih.gov/pubmed/11274424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061408298
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https://ncbi.nlm.nih.gov/pmc/articles/PMC31169/
https://ncbi.nlm.nih.gov/pubmed/11274424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061408298

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