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Echinomycin and distamycin induce rotation of nucleosome core DNA.

When nucleosome cores reconstituted from chicken erythrocyte histones and a 160 bp DNA molecule are exposed to echinomycin, a bis-intercalating antitumour antibiotic, the DNA appears to rotate with respect to the histone octamer by about half a turn. New bands appear in patterns of DNAase I digestio...

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Autors principals: Low, C M, Drew, H R, Waring, M J
Format: Article
Idioma:en
Publicat: 1986
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC311699/
https://ncbi.nlm.nih.gov/pubmed/3763391
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