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An alternative protein splicing mechanism for inteins lacking an N-terminal nucleophile

Variations in the intein-mediated protein splicing mechanism are becoming more apparent as polymorphisms in conserved catalytic residues are identified. The conserved Ser or Cys at the intein N-terminus and the conserved intein penultimate His are absent in the KlbA family of inteins. These inteins...

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Detalhes bibliográficos
Main Authors: Southworth, Maurice W., Benner, Jack, Perler, Francine B.
Formato: Artigo
Idioma:en
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC314217/
https://ncbi.nlm.nih.gov/pubmed/10990465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.18.5019
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