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TRIP6 and LPP, but not Zyxin, are present at a subset of telomeres in human cells

The protection of chromosome ends requires the inhibition of DNA damage responses at telomeres. This inhibition is exerted in great part by the shelterin complex, known to prevent inappropriate ATM and ATR activation. The molecular mechanisms by which shelterin protects telomeres are incompletely un...

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Format: Artikel
Sprache:en
Veröffentlicht: Landes Bioscience 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142457/
https://ncbi.nlm.nih.gov/pubmed/21519191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.11.15676
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