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Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP
Mice with monoallelic inactivation of the CBP gene develop highly penetrant, multilineage defects in hematopoietic differentiation and, with advancing age, an increased incidence of hematologic malignancies. The latter are characterized, at least in some cases, by loss of heterozygosity (LOH) at the...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | en |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC316359/ https://ncbi.nlm.nih.gov/pubmed/10673499 |
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