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The Infectivity of prM-Containing Partially Mature West Nile Virus Does Not Require the Activity of Cellular Furin-Like Proteases
Cleavage of the flavivirus prM protein by a cellular furin-like protease is a hallmark of virion maturation. While this cleavage is a required step in the viral life cycle, it can be inefficient. Virions that retain uncleaved prM may be infectious. We investigated whether cleavage by furin of prM on...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
American Society for Microbiology
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3209279/ https://ncbi.nlm.nih.gov/pubmed/21880759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05559-11 |
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