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Nucleolar NF-κB/RelA mediates apoptosis by causing cytoplasmic relocalization of nucleophosmin

In a number of contexts, and particularly in response to cellular stress, stimulation of the NF-kappaB (NF-κB) pathway promotes apoptosis. One mechanism underlying this pro-apoptotic activity is nucleolar sequestration of RelA, which is reported to cause cell death by repressing NF-κB-driven transcr...

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Formato: Artigo
Idioma:en
Publicado em: Nature Publishing Group 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214916/
https://ncbi.nlm.nih.gov/pubmed/21660047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.79
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