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Hypertrophic gastropathy resembling Ménétrier's disease in transgenic mice overexpressing transforming growth factor alpha in the stomach.

Transforming growth factor alpha (TGF alpha) is thought to participate in the normal and pathologic processes of numerous tissues, including the gastric mucosa. To explore its role in vivo, transgenic mice were generated overexpressing TGF alpha in the stomach. TGF alpha induced dramatic structural...

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Detalhes bibliográficos
Main Authors: Takagi, H, Jhappan, C, Sharp, R, Merlino, G
Formato: Artigo
Idioma:en
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC329980/
https://ncbi.nlm.nih.gov/pubmed/1522224
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