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Naturally variant autosomal and sex-linked loci determine the severity of iron overload in β(2)-microglobulin-deficient mice

Hereditary hemochromatosis (HH) is a common chronic human genetic disorder whose hallmark is systemic iron overload. Homozygosity for a mutation in the MHC class I heavy chain paralogue gene HFE has been found to be a primary cause of HH. However, many individuals homozygous for the defective allele...

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Detalhes bibliográficos
Main Authors:	Sproule, Thomas J., Jazwinska, Elizabeth C., Britton, Robert S., Bacon, Bruce R., Fleming, Robert E., Sly, William S., Roopenian, Derry C., Nakanishi, Atsushi, Morita, Shigeru, Iwashita, Hiroki, Sagiya, Yoji, Ashida, Yasuko, Shirafuji, Hideo, Fujisawa, Yukio, Nishimura, Osamu, Fujino, Masahiko, Mittelman, Moshe, Neumann, Drorit, Peled, Alpha, Kanter, Pazit, Haran-Ghera, Nechama, Zabolotny, Janice M., Kim, Young-Bum, Peroni, Odile D., Kim, Jason K., Pani, Michael A., Boss, Olivier, Klaman, Lori D., Kamatkar, Shubhangi, Shulman, Gerald I., Kahn, Barbara B., Neel, Benjamin G., Robbins, Paul B., Lin, Qun, Goodnough, Julia B., Tian, Hongsheng, Chen, Xinjian, Khavari, Paul A., Gonzalez, Enrique, Dhanda, Rahul, Bamshad, Mike, Mummidi, Srinivas, Geevarghese, Reni, Catano, Gabriel, Anderson, Stephanie A., Walter, Elizabeth A., Stephan, Kevin T., Hammer, Michael F., Mangano, Andrea, Sen, Luisa, Clark, Robert A., Ahuja, Seema S., Dolan, Matthew J., Ahuja, Sunil K., Auricchio, Alberto, Zhou, Rong, Wilson, James M., Glickson, Jerry D., Holla, Vijaykumar R., Adas, Fadi, Imig, John D., Zhao, Xueying, Price, Edward, Olsen, Nancy, Kovacs, William J., Magnuson, Mark A., Keeney, Diane S., Breyer, Matthew D., Falck, John R., Waterman, Michael R., Capdevila, Jorge H., Morton, N. E., Zhang, W., Taillon-Miller, P., Ennis, S., Kwok, P.-Y., Collins, A., Mayer, D. C. Ghislaine, Kaneko, Osamu, Hudson-Taylor, Diana E., Reid, Marion E., Miller, Louis H., Lal, Altaf A., Patterson, Pamela S., Sacci, John B., Vaughan, Jefferson A., Paul, Chris, Collins, William E., Wirtz, Robert A., Azad, Abdu F., Zhu, Peixuan, van der Ende, Arie, Falush, Daniel, Brieske, Norbert, Morelli, Giovanna, Linz, Bodo, Popovic, Tanja, Schuurman, Ilse G. A., Adegbola, Richard A., Zurth, Kerstin, Gagneux, Sébastien, Platonov, Alexander E., Riou, Jean-Yves, Caugant, Dominique A., Nicolas, Pierre, Achtman, Mark, Karlin, Samuel, Mrázek, Jan, Muriaux, Delphine, Mirro, Jane, Harvin, Demetria, Rein, Alan, Yang, Zhiyong, Shimpi, Amita, Purves, Dale, Lin, Ridwan, Karpa, Kelly, Kabbani, Nadine, Goldman-Rakic, Patricia, Levenson, Robert, Yu, Tzu-ping, McKinney, Sheri, Lester, Henry A., Davidson, Norman, Zirlinger, Mariela, Kreiman, Gabriel, Anderson, David J., Hess, Dietmar, El Manira, Abdeljabbar, Horn, Gabriel, Nicol, Alister U., Brown, Malcolm W., Khakh, Baljit S., Smith, W. Bryan, Chiu, Chi-Sung, Ju, Donghong, Panizzutti, Rogério, De Miranda, Joari, Ribeiro, Cátia S., Engelender, Simone, Wolosker, Herman, Sora, Ichiro, Hall, F. Scott, Andrews, Anne M., Itokawa, Masanari, Li, Xiao-Fei, Wei, Hong-Bing, Wichems, Christine, Lesch, Klaus-Peter, Murphy, Dennis L., Uhl, George R., Oliver, William R., Shenk, Jennifer L., Snaith, Mike R., Russell, Caroline S., Plunket, Kelli D., Bodkin, Noni L., Lewis, Michael C., Winegar, Deborah A., Sznaidman, Marcos L., Lambert, Millard H., Xu, H. Eric, Sternbach, Daniel D., Kliewer, Steven A., Hansen, Barbara C., Willson, Timothy M., Snyder, James P., Nettles, James H., Cornett, Ben, Downing, Kenneth H., Nogales, Eva, Rocha, Gerson M., Michea, Luis F., Peters, Eugenia M., Kirby, Martha, Xu, Yuhui, Ferguson, Douglas R., Burg, Maurice B., Ino, Mitsuhiro, Yoshinaga, Takashi, Wakamori, Minoru, Miyamoto, Norimasa, Takahashi, Eiki, Sonoda, Jiro, Kagaya, Takaki, Oki, Tohru, Nagasu, Takeshi, Nishizawa, Yukio, Tanaka, Isao, Imoto, Keiji, Aizawa, Shinichi, Koch, Sheryl, Schwartz, Arnold, Niidome, Tetsuhiro, Sawada, Kohei, Mori, Yasuo, Vázquez, Esther, Nobles, Muriel, Valverde, Miguel A., Hoppe, Uta C., Marbán, Eduardo, Johns, David C., Xiang, Youbin, Zhang, Jun, Weeks, Donald P., Fukuzawa, Hideya, Miura, Kenji, Ishizaki, Kimitsune, Kucho, Ken-ichi, Saito, Tatsuaki, Kohinata, Tsutomu, Ohyama, Kanji, Schmid, Markus, Simpson, David J., Sarioglu, Hakan, Lottspeich, Friedrich, Gietl, Christine, Hampton, Robert R., Carrasco, Marisa, McElree, Brian, Willard, Huntington F., Gridley, Thomas, Breivik, Jarle, MacHugh, David E., Bradley, Daniel G., Karsenty, G., Myers, Norman, Knoll, Andrew H., Jablonski, David, Erwin, Douglas H., Rosenzweig, Michael L., Jackson, Jeremy B. C., Knowlton, Nancy, Templeton, Alan R., Robertson, Robert J., Brisson, Jennifer, Strasburg, Jared, Tilman, David, Lehman, Clarence, Bazzaz, F. A., Mooney, H. A., Cleland, E. E.
Formato:	Artigo
Idioma:	English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English
Publicado em:	The National Academy of Sciences 2001
Assuntos:	Biological Sciences Commentary From the Academy Colloquium Paper
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Naturally variant autosomal and sex-linked loci determine the severity of iron overload in β(2)-microglobulin-deficient mice

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