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Phosphorylation of ORC2 Protein Dissociates Origin Recognition Complex from Chromatin and Replication Origins
During the late M to the G(1) phase of the cell cycle, the origin recognition complex (ORC) binds to the replication origin, leading to the assembly of the prereplicative complex for subsequent initiation of eukaryotic chromosome replication. We found that the cell cycle-dependent phosphorylation of...
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| Lingua: | en |
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American Society for Biochemistry and Molecular Biology
2012
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3320937/ https://ncbi.nlm.nih.gov/pubmed/22334659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.338467 |
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