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CHANGES IN CHROMOSOMES OF BONE MARROW AFTER INTRAVENOUS INJECTIONS OF 7,12-DIMETHYLBENZ(A)ANTHRACENE AND RELATED COMPOUNDS

Multiple intravenous injections of an emulsion containing 7,12-dimethylbenz(a)anthracene (DMBA) or 7,8,12-trimethylbenz(a)anthracene (TMBA) induce a high incidence of leukemia in rats. Twenty-four hours after a single injection, about half of the metaphase cells in the marrow have chromosomes with b...

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Detalhes bibliográficos
Main Authors: Rees, E. Douglas, Majumdar, S. K., Shuck, Amy
Formato: Artigo
Idioma:en
Publicado em: 1970
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC335810/
https://ncbi.nlm.nih.gov/pubmed/5273451
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