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Acetylation of Retinal Histones in Diabetes Increases Inflammatory Proteins: EFFECTS OF MINOCYCLINE AND MANIPULATION OF HISTONE ACETYLTRANSFERASE (HAT) AND HISTONE DEACETYLASE (HDAC)
Histone acetylation was significantly increased in retinas from diabetic rats, and this acetylation was inhibited in diabetics treated with minocycline, a drug known to inhibit early diabetic retinopathy in animals. Histone acetylation and expression of inflammatory proteins that have been implicate...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3406672/ https://ncbi.nlm.nih.gov/pubmed/22648458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.375204 |
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