Tolerance of human MSH2(+/−) lymphoblastoid cells to the methylating agent temozolomide

Members of hereditary nonpolyposis colon cancer (HNPCC) families harboring heterozygous germline mutations in the DNA mismatch repair genes hMSH2 or hMLH1 present with tumors generally two to three decades earlier than individuals with nonfamilial sporadic colon cancer. We searched for phenotypic fe...

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Detalhes bibliográficos
Main Authors: Marra, Giancarlo, D'Atri, Stefania, Corti, Chantal, Bonmassar, Laura, Cattaruzza, Maria Sofia, Schweizer, Pascal, Heinimann, Karl, Bartosova, Zdena, Nyström-Lahti, Minna, Jiricny, Josef
Formato: Artigo
Idioma:en
Publicado em: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC34640/
https://ncbi.nlm.nih.gov/pubmed/11416201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.121136498
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https://ncbi.nlm.nih.gov/pmc/articles/PMC34640/
https://ncbi.nlm.nih.gov/pubmed/11416201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.121136498

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