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Vertical T cell immunodominance and epitope entropy determine HIV-1 escape
HIV-1 accumulates mutations in and around reactive epitopes to escape recognition and killing by CD8(+) T cells. Measurements of HIV-1 time to escape should therefore provide information on which parameters are most important for T cell–mediated in vivo control of HIV-1. Primary HIV-1–specific T cel...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
American Society for Clinical Investigation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3533301/ https://ncbi.nlm.nih.gov/pubmed/23221345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65330 |
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