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Polyamine-based small molecule epigenetic modulators
Chromatin remodelling enzymes such as the histone deacetylases (HDACs) and histone demethylases such as lysine-specific demethylase 1 (LSD1) have been validated as targets for cancer drug discovery. Although a number of HDAC inhibitors have been marketed or are in human clinical trials, the search f...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3535317/ https://ncbi.nlm.nih.gov/pubmed/23293738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C1MD00220A |
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