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mTOR inhibitors block Kaposi sarcoma growth by inhibiting essential autocrine growth factors and tumor angiogenesis
Kaposi’s Sarcoma (KS) originates from endothelial cells and it is one of the most overt angiogenic tumors. In Sub-Saharan Africa, where HIV and the Kaposi Sarcoma-associated Herpes Virus (KSHV) are endemic, KS is the most common cancer overall, but model systems for disease study are insufficient. H...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3618543/ https://ncbi.nlm.nih.gov/pubmed/23382046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-1851 |
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