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Regulation of the transcript for a lysosomal protein: evidence for a gene program modified by platelet-derived growth factor.

Platelet-derived growth factor (PDGF) stimulates density-arrested BALB/c-3T3 cells to synthesize MEP, a lysosomal protein. This enhanced synthesis appears to be largely regulated by the PDGF-modulated accumulation of MEP mRNA, a 1.8-kilobase species. The increase in the MEP transcript, which is depe...

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Bibliographic Details
Main Authors: Frick, K K, Doherty, P J, Gottesman, M M, Scher, C D
Format: Article
Language:en
Published: 1985
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC366993/
https://ncbi.nlm.nih.gov/pubmed/3915532
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