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Increased Clearance and Degradation of [(3)H]Insulin in Streptozotocin Diabetic Rats: ROLE OF THE INSULIN-RECEPTOR COMPARTMENT

The role of the insulin-receptor compartment in the pharmacokinetics of intravenously injected insulin in rats was studied. Since streptozotocin-diabetes in rats results in increased insulin binding to tissues in vitro, insulin pharmacokinetics in streptozotocin-diabetic rats were compared to contro...

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Detalhes bibliográficos
Main Authors: Philippe, Jacques, Halban, Philippe A., Gjinovci, Asllan, Duckworth, William C., Estreicher, Jurek, Renold, Albert E.
Formato: Artigo
Idioma:en
Publicado em: 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC370616/
https://ncbi.nlm.nih.gov/pubmed/6451633
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