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Network-guided sparse regression modeling for detection of gene-by-gene interactions
Motivation: Genetic variants identified by genome-wide association studies to date explain only a small fraction of total heritability. Gene-by-gene interaction is one important potential source of unexplained total heritability. We propose a novel approach to detect such interactions that uses pena...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
Oxford University Press
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3711507/ https://ncbi.nlm.nih.gov/pubmed/23599501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt139 |
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