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Influences on Trimerization and Aggregation of Soluble, Cleaved HIV-1 SOSIP Envelope Glycoprotein
We describe methods to improve the properties of soluble, cleaved gp140 trimers of the human immunodeficiency virus type 1 (HIV-1) envelope glycoproteins (Env) for use in structural studies and as immunogens. In the absence of nonionic detergents, gp140 of the KNH1144 genotype, terminating at residu...
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| Format: | Article |
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| Language: | en |
| Published: |
American Society for Microbiology
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3754145/ https://ncbi.nlm.nih.gov/pubmed/23824824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01226-13 |
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