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IL-6 increases B-cell IgG production in a feed-forward proinflammatory mechanism to skew hematopoiesis and elevate myeloid production
Src homology 2 domain-containing inositol 5-phosphatase (SHIP(−/−)) animals display an age-related increase in interleukin-6 (IL-6), a decrease in B lymphopoiesis, and an elevation in myelopoiesis. We investigated the origin of the IL-6 production and show that it is largely produced by peritoneal a...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
American Society of Hematology
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3790945/ https://ncbi.nlm.nih.gov/pubmed/20351305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-230631 |
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