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Identification in pituitary tissue of a peptide alpha-amidation activity that acts on glycine-extended peptides and requires molecular oxygen, copper, and ascorbic acid.

An enzymatic activity capable of producing an alpha-amidated peptide product from its glycine-extended precursor has been identified in secretory granules of rat anterior, intermediate, and neural pituitary and bovine intermediate pituitary. High levels of endogenous inhibitors of this alpha-amidati...

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Detalhes bibliográficos
Main Authors: Eipper, B A, Mains, R E, Glembotski, C C
Formato: Artigo
Idioma:en
Publicado em: 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC384206/
https://ncbi.nlm.nih.gov/pubmed/6576381
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