Inherited Interleukin-12 Deficiency: IL12B Genotype and Clinical Phenotype of 13 Patients from Six Kindreds

Interleukin-12 (IL12) is a cytokine that is secreted by activated phagocytes and dendritic cells and that induces interferon-γ production by natural-killer and T lymphocytes. It consists of two subunits, p35 and p40, which are encoded by IL12A and IL12B, respectively. The first reported patient with...

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Main Authors: Picard, Capucine, Fieschi, Claire, Altare, Frédéric, Al-Jumaah, Suliman, Al-Hajjar, Sami, Feinberg, Jacqueline, Dupuis, Stéphanie, Soudais, Claire, Al-Mohsen, Ibrahim Zaid, Génin, Emmanuelle, Lammas, David, Kumararatne, Dinakantha S., Leclerc, Tony, Rafii, Arash, Frayha, Husn, Murugasu, Belinda, Wah, Lee Bee, Sinniah, Raja, Loubser, Michael, Okamoto, Emi, Al-Ghonaium, Abdulaziz, Tufenkeji, Haysam, Abel, Laurent, Casanova, Jean-Laurent
Formato: Artigo
Idioma:en
Publicado em: The American Society of Human Genetics 2002
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC384913/
https://ncbi.nlm.nih.gov/pubmed/11753820
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https://ncbi.nlm.nih.gov/pmc/articles/PMC384913/
https://ncbi.nlm.nih.gov/pubmed/11753820

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