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Effects of pH on the structure and function of carboxypeptidase A: crystallographic studies.

High-resolution crystal structures are described for carboxypeptidase A (EC 3.4.17.1) in crystals grown at pH 8.5, 9.0, and 9.5 and compared with the structure at pH 7.5. The comparison shows that in the pH range of 7.5-9.5 the enzyme structure is practically unchanged, and, most importantly, that t...

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Detalhes bibliográficos
Main Authors: Shoham, G, Rees, D C, Lipscomb, W N
Formato: Artigo
Idioma:en
Publicado em: 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC392233/
https://ncbi.nlm.nih.gov/pubmed/6595659
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