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N-myc transgene promotes B lymphoid proliferation, elicits lymphomas and reveals cross-regulation with c-myc.
To assess the impact of constitutive N-myc expression on lymphocytes, we generated lines of transgenic mice bearing the murine N-myc oncogene coupled to the immunoglobulin heavy chain enhancer (E mu). As in mice carrying an analogous c-myc construct, E mu-N-myc mice exhibit a limited overgrowth of c...
में बचाया:
| मुख्य लेखकों: | , , , , |
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| स्वरूप: | लेख |
| भाषा: | en |
| प्रकाशित: |
1989
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC400871/ https://ncbi.nlm.nih.gov/pubmed/2785918 |
| टैग : |
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