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Analysis of BRCA1and BRCA2 large genomic rearrangements in Sri Lankan familial breast cancer patients and at risk individuals

BACKGROUND: Majority of mutations found to date in the BRCA1/BRCA2 genes in breast and/or ovarian cancer families are point mutations or small insertions and deletions scattered over the coding sequence and splice junctions. Such mutations and sequence variants of BRCA1 and BRCA2 genes were previous...

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Formato: Artigo
Idioma:en
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057568/
https://ncbi.nlm.nih.gov/pubmed/24906410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-344
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