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Down syndrome-critical region contains a gene homologous to Drosophila sim expressed during rat and human central nervous system development.
Many features of Down syndrome might result from the overdosage of only a few genes located in a critical region of chromosome 21. To search for these genes, cosmids mapping in this region were isolated and used for trapping exons. One of the trapped exons obtained has a sequence very similar to par...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | en |
| Publicado em: |
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC40950/ https://ncbi.nlm.nih.gov/pubmed/7568099 |
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