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Functional evidence for active site location of tetrameric thymidylate synthase X at the interphase of three monomers
Little is known about the catalytic mechanism of the recently discovered ThyX family of flavin-dependent thymidylate synthases that are required for thymidylate (deoxythymidine 5′-monophosphate) synthesis in a large number of microbial species. Using a combination of site-directed mutagenesis and bi...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | en |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC409905/ https://ncbi.nlm.nih.gov/pubmed/15123820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401365101 |
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