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Antitrypanosomal Activity of Fexinidazole Metabolites, Potential New Drug Candidates for Chagas Disease
This study was designed to verify the in vivo efficacy of sulfoxide and sulfone fexinidazole metabolites following oral administration in a murine model of Chagas disease. Female Swiss mice infected with the Y strain of Trypanosoma cruzi were treated orally once per day with each metabolite at doses...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
American Society for Microbiology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4136024/ https://ncbi.nlm.nih.gov/pubmed/24841257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02754-13 |
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