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Perinatal systemic gene delivery using adeno-associated viral vectors

Neurodegenerative monogenic diseases often affect tissues and organs beyond the nervous system. An effective treatment would require a systemic approach. The intravenous administration of novel therapies is ideal but is hampered by the inability of such drugs to cross the blood–brain barrier (BBB) a...

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Detalhes bibliográficos
Formato: Artigo
Idioma:en
Publicado em: Frontiers Media S.A. 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231876/
https://ncbi.nlm.nih.gov/pubmed/25452713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2014.00089
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