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Gene therapy for hemophilia A: production of therapeutic levels of human factor VIII in vivo in mice.
Continuous delivery of factor VIII (FVIII) protein in hemophiliacs by gene therapy will represent a major clinical advance over the current practice of infrequent administration of purified FVIII. Conceptually, retroviral vectors that can permanently insert the FVIII gene into the DNA of the host ce...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | en |
| Publicado em: |
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC42629/ https://ncbi.nlm.nih.gov/pubmed/7862626 |
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