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Functional analysis of myosin missense mutations in familial hypertrophic cardiomyopathy.

To analyze potential functional consequences of myosin heavy chain (MHC) mutations identified in patients with familial hypertrophic cardiomyopathy (FHC), we have assessed the stability of the mutant MHCs and their ability to form thick filaments. Constructs encoding wild-type rat alpha MHC and seve...

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Detalhes bibliográficos
Main Authors:	Straceski, A J, Geisterfer-Lowrance, A, Seidman, C E, Seidman, J G, Leinwand, L A, Wan, K M, Nickerson, J A, Krockmalnic, G, Penman, S, Chow, M, Yao, A, Rubin, H, Haba, S, Nisonoff, A, Dong, Z, Birrer, M J, Watts, R G, Matrisian, L M, Colburn, N H, Toyonaga, T, Hino, O, Sugai, S, Wakasugi, S, Abe, K, Shichiri, M, Yamamura, K, de Bruin, D, Lanzer, M, Ravetch, J V, Huang, X Y, Morielli, A D, Peralta, E G, Hiesel, R, Combettes, B, Brennicke, A, von Haeseler, A, Wong, K K, McClelland, M, Cook, T A, Urrutia, R, McNiven, M A, Swarzenski, B C, Tang, L, Oh, Y J, O'Malley, K L, Todd, R D, Lang, M, Treinies, I, Duesberg, P H, Kurth, R, Cichutek, K, Chu, S, Archer, R H, Zengel, J M, Lindahl, L, Fawell, S, Seery, J, Daikh, Y, Moore, C, Chen, L L, Pepinsky, B, Barsoum, J, Delaney, K R, Gelperin, A, Fee, M S, Flores, J A, Gervais, R, Tank, D W, Kleinfeld, D, Wu, J C, Merlino, G, Fausto, N, Larkum, A W, Scaramuzzi, C, Cox, G C, Hiller, R G, Turner, A G, Berardi, N, Cellerino, A, Domenici, L, Fagiolini, M, Pizzorusso, T, Cattaneo, A, Maffei, L, Zettl, R, Schell, J, Palme, K, Jasper, F, Koncz, C, Steinbiss, H H, Wang, Z, Harshey, R M, Tang, X S, Diner, B A, Larsen, B S, Gilchrist, M L, Lorigan, G A, Britt, R D, Hinds, P W, Dowdy, S F, Eaton, E N, Arnold, A, Weinberg, R A, Westendorf, J M, Rao, P N, Gerace, L, Clark, A G, Silveria, S, Meyers, W, Langley, C H, Pena, S D, de Souza, K T, de Andrade, M, Chakraborty, R, Ioffe, E, Stanley, P, Newman, J F, Piatti, P G, Gorman, B M, Burrage, T G, Ryan, M D, Flint, M, Brown, F, Liu, L, Simon, S A, Wu, X, Wakamiya, M, Vaishnav, S, Geske, R, Montgomery, C, Jones, P, Bradley, A, Caskey, C T, Tajbakhsh, S, Buckingham, M E, Ray, A, Prefontaine, K E, Fontana, W, Buss, L W, Hoff, C M, Ghosh, A K, Prabhakar, B S, Jacob, S T, Gautam, A M, Lock, C B, Smilek, D E, Pearson, C I, Steinman, L, McDevitt, H O, Miller, C L, Lee, J H, Kieff, E, Longnecker, R, Staubli, U, Rogers, G, Lynch, G, Aguila, M C, Pierpaoli, W, Regelson, W, Benedetti, A, Strazzabosco, M, Ng, O C, Boyer, J L, Rose, D W, Saltiel, A R, Majumdar, M, Decker, S J, Olefsky, J M, Yu, Y T, Snyder, L, Pastor, A M, De la Cruz, R R, Baker, R, Kelly, K J, Williams, W W, Colvin, R B, Bonventre, J V, Nayal, M, Di Cera, E, Unsal, H, Yakicier, C, Marçais, C, Kew, M, Volkmann, M, Zentgraf, H, Isselbacher, K J, Ozturk, M, Chang, B H, Shimmin, L C, Shyue, S K, Hewett-Emmett, D, Li, W H, Gilbert, C D
Formato:	Artigo
Idioma:	English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English
Publicado em:	1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.gov/pmc/articles/PMC42994/ https://ncbi.nlm.nih.gov/pubmed/8290568 https://ncbi.nlm.nih.gov/pmc/articles/PMC42995/ https://ncbi.nlm.nih.gov/pubmed/8290569 https://ncbi.nlm.nih.gov/pmc/articles/PMC42996/ https://ncbi.nlm.nih.gov/pubmed/8290570 https://ncbi.nlm.nih.gov/pmc/articles/PMC42997/ https://ncbi.nlm.nih.gov/pubmed/7507250 https://ncbi.nlm.nih.gov/pmc/articles/PMC42998/ https://ncbi.nlm.nih.gov/pubmed/8290571 https://ncbi.nlm.nih.gov/pmc/articles/PMC42999/ https://ncbi.nlm.nih.gov/pubmed/8290572 https://ncbi.nlm.nih.gov/pmc/articles/PMC43000/ https://ncbi.nlm.nih.gov/pubmed/8290573 https://ncbi.nlm.nih.gov/pmc/articles/PMC43001/ https://ncbi.nlm.nih.gov/pubmed/8290574 https://ncbi.nlm.nih.gov/pmc/articles/PMC43002/ https://ncbi.nlm.nih.gov/pubmed/8290575 https://ncbi.nlm.nih.gov/pmc/articles/PMC43003/ https://ncbi.nlm.nih.gov/pubmed/7507251 https://ncbi.nlm.nih.gov/pmc/articles/PMC43004/ https://ncbi.nlm.nih.gov/pubmed/7507252 https://ncbi.nlm.nih.gov/pmc/articles/PMC43005/ https://ncbi.nlm.nih.gov/pubmed/8290576 https://ncbi.nlm.nih.gov/pmc/articles/PMC43006/ https://ncbi.nlm.nih.gov/pubmed/7904756 https://ncbi.nlm.nih.gov/pmc/articles/PMC43007/ https://ncbi.nlm.nih.gov/pubmed/8290577 https://ncbi.nlm.nih.gov/pmc/articles/PMC43008/ https://ncbi.nlm.nih.gov/pubmed/8290578 https://ncbi.nlm.nih.gov/pmc/articles/PMC43009/ https://ncbi.nlm.nih.gov/pubmed/8290579 https://ncbi.nlm.nih.gov/pmc/articles/PMC43010/ https://ncbi.nlm.nih.gov/pubmed/8290580 https://ncbi.nlm.nih.gov/pmc/articles/PMC43011/ https://ncbi.nlm.nih.gov/pubmed/7904757 https://ncbi.nlm.nih.gov/pmc/articles/PMC43012/ https://ncbi.nlm.nih.gov/pubmed/11607451 https://ncbi.nlm.nih.gov/pmc/articles/PMC43013/ https://ncbi.nlm.nih.gov/pubmed/8290581 https://ncbi.nlm.nih.gov/pmc/articles/PMC43014/ https://ncbi.nlm.nih.gov/pubmed/8290582 https://ncbi.nlm.nih.gov/pmc/articles/PMC43015/ https://ncbi.nlm.nih.gov/pubmed/8290583 https://ncbi.nlm.nih.gov/pmc/articles/PMC43016/ https://ncbi.nlm.nih.gov/pubmed/8290584 https://ncbi.nlm.nih.gov/pmc/articles/PMC43017/ https://ncbi.nlm.nih.gov/pubmed/8290585 https://ncbi.nlm.nih.gov/pmc/articles/PMC43018/ https://ncbi.nlm.nih.gov/pubmed/8290586 https://ncbi.nlm.nih.gov/pmc/articles/PMC43019/ https://ncbi.nlm.nih.gov/pubmed/8290587 https://ncbi.nlm.nih.gov/pmc/articles/PMC43020/ https://ncbi.nlm.nih.gov/pubmed/8290588 https://ncbi.nlm.nih.gov/pmc/articles/PMC43021/ https://ncbi.nlm.nih.gov/pubmed/8290589 https://ncbi.nlm.nih.gov/pmc/articles/PMC43022/ https://ncbi.nlm.nih.gov/pubmed/8290590 https://ncbi.nlm.nih.gov/pmc/articles/PMC43023/ https://ncbi.nlm.nih.gov/pubmed/8290591 https://ncbi.nlm.nih.gov/pmc/articles/PMC43024/ https://ncbi.nlm.nih.gov/pubmed/8290592 https://ncbi.nlm.nih.gov/pmc/articles/PMC43025/ https://ncbi.nlm.nih.gov/pubmed/8290593 https://ncbi.nlm.nih.gov/pmc/articles/PMC43026/ https://ncbi.nlm.nih.gov/pubmed/8290594 https://ncbi.nlm.nih.gov/pmc/articles/PMC43027/ https://ncbi.nlm.nih.gov/pubmed/8290595 https://ncbi.nlm.nih.gov/pmc/articles/PMC43028/ https://ncbi.nlm.nih.gov/pubmed/8290596 https://ncbi.nlm.nih.gov/pmc/articles/PMC43029/ https://ncbi.nlm.nih.gov/pubmed/8290597 https://ncbi.nlm.nih.gov/pmc/articles/PMC43030/ https://ncbi.nlm.nih.gov/pubmed/7507253 https://ncbi.nlm.nih.gov/pmc/articles/PMC43031/ https://ncbi.nlm.nih.gov/pubmed/8290598 https://ncbi.nlm.nih.gov/pmc/articles/PMC43032/ https://ncbi.nlm.nih.gov/pubmed/8290599 https://ncbi.nlm.nih.gov/pmc/articles/PMC43033/ https://ncbi.nlm.nih.gov/pubmed/7904758 https://ncbi.nlm.nih.gov/pmc/articles/PMC43034/ https://ncbi.nlm.nih.gov/pubmed/8290600 https://ncbi.nlm.nih.gov/pmc/articles/PMC43035/ https://ncbi.nlm.nih.gov/pubmed/8290601 https://ncbi.nlm.nih.gov/pmc/articles/PMC43036/ https://ncbi.nlm.nih.gov/pubmed/8290602 https://ncbi.nlm.nih.gov/pmc/articles/PMC43037/ https://ncbi.nlm.nih.gov/pubmed/8290603 https://ncbi.nlm.nih.gov/pmc/articles/PMC43038/ https://ncbi.nlm.nih.gov/pubmed/8290604 https://ncbi.nlm.nih.gov/pmc/articles/PMC43039/ https://ncbi.nlm.nih.gov/pubmed/7904759 https://ncbi.nlm.nih.gov/pmc/articles/PMC43040/ https://ncbi.nlm.nih.gov/pubmed/8290605 https://ncbi.nlm.nih.gov/pmc/articles/PMC43041/ https://ncbi.nlm.nih.gov/pubmed/8290606 https://ncbi.nlm.nih.gov/pmc/articles/PMC43042/ https://ncbi.nlm.nih.gov/pubmed/8290607 https://ncbi.nlm.nih.gov/pmc/articles/PMC43123/ https://ncbi.nlm.nih.gov/pubmed/8108386
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Functional analysis of myosin missense mutations in familial hypertrophic cardiomyopathy.

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