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Defective PDI release from platelets and endothelial cells impairs thrombus formation in Hermansky-Pudlak syndrome
Protein disulfide isomerase (PDI), secreted from platelets and endothelial cells after injury, is required for thrombus formation. The effect of platelet and endothelial cell granule contents on PDI-mediated thrombus formation was studied by intravital microscopy using a mouse model of Hermansky-Pud...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
American Society of Hematology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4351508/ https://ncbi.nlm.nih.gov/pubmed/25593336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-08-597419 |
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