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Expanding our Understanding of Sequence-Function Relationships of Type II Polyketide Biosynthetic Gene Clusters: Bioinformatics-Guided Identification of Frankiamicin A from Frankia sp. EAN1pec

A large and rapidly increasing number of unstudied “orphan” natural product biosynthetic gene clusters are being uncovered in sequenced microbial genomes. An important goal of modern natural products research is to be able to accurately predict natural product structures and biosynthetic pathways fr...

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Detalhes bibliográficos
Formato: Artigo
Idioma:en
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383371/
https://ncbi.nlm.nih.gov/pubmed/25837682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121505
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