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Extracellular ATP induces oscillations of intracellular Ca(2+) and membrane potential and promotes transcription of IL-6 in macrophages

The effects of low concentrations of extracellular ATP on cytosolic Ca(2+), membrane potential, and transcription of IL-6 were studied in monocyte-derived human macrophages. During inflammation or infection many cells secrete ATP. We show here that application of 10 μM ATP or 10 μM UTP induces oscil...

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Detalhes bibliográficos
Main Authors: Hanley, Peter J., Musset, Boris, Renigunta, Vijay, Limberg, Sven H., Dalpke, Alexander H., Sus, Rainer, Heeg, Klaus M., Preisig-Müller, Regina, Daut, Jürgen
Formato: Artigo
Idioma:en
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC439002/
https://ncbi.nlm.nih.gov/pubmed/15194822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400733101
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