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Phosphodiesterase 3 (PDE3) inhibition with Cilostazol does not block in vivo oocyte maturation in rhesus macaques (Macaca mulatta)
OBJECTIVE: Studies in mice suggest that cilostazol, an FDA-approved phosphodiesterase 3 (PDE3) inhibitor, might have a contraceptive effect within the approved dose range. We sought to evaluate the potential contraceptive effects of cilostazol in a non-human primate model. STUDY DESIGN: Adult female...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
2015
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4417033/ https://ncbi.nlm.nih.gov/pubmed/25645461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.contraception.2015.01.017 |
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