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Antiviral Action of Camptothecin

At a concentration of 10 μm, camptothecin inhibited vaccinia deoxyribonucleic acid (DNA) synthesis in HeLa cells. Inhibition of viral DNA synthesis was observed when the drug was added before infection or at 1 or 2 hr after infection. Inhibitory effects of camptothecin on vaccinia DNA synthesis coul...

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Detalhes bibliográficos
Main Authors: Horwitz, Susan B., Chang, Chung-Ke, Grollman, Arthur P.
Formato: Artigo
Idioma:en
Publicado em: 1972
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC444326/
https://ncbi.nlm.nih.gov/pubmed/4363789
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