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Metabolic Engineering of Mannitol Production in Lactococcus lactis: Influence of Overexpression of Mannitol 1-Phosphate Dehydrogenase in Different Genetic Backgrounds

To obtain a mannitol-producing Lactococcus lactis strain, the mannitol 1-phosphate dehydrogenase gene (mtlD) from Lactobacillus plantarum was overexpressed in a wild-type strain, a lactate dehydrogenase(LDH)-deficient strain, and a strain with reduced phosphofructokinase activity. High-performance l...

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Detalhes bibliográficos
Main Authors: Wisselink, H. Wouter, Mars, Astrid E., van der Meer, Pieter, Eggink, Gerrit, Jeroen Hugenholtz
Formato: Artigo
Idioma:English
Publicado em: American Society for Microbiology 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC444806/
https://ncbi.nlm.nih.gov/pubmed/15240312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.70.7.4286-4292.2004
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