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ADF/cofilin-actin rods in neurodegenerative diseases

Dephosphorylation (activation) of cofilin, an actin binding protein, is stimulated by initiators of neuronal dysfunction and degeneration including oxidative stress, excitotoxic glutamate, ischemia, and soluble forms of β-amyloid peptide (Aβ). Hyperactive cofilin forms rod-shaped cofilin-saturated a...

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Detalhes bibliográficos
Formato: Artigo
Idioma:en
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458070/
https://ncbi.nlm.nih.gov/pubmed/20088812
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