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NMR structure of a biologically active peptide containing the RNA-binding domain of human immunodeficiency virus type 1 Tat.

The Tat protein of human immunodeficiency virus type 1 enhances transcription by binding to a specific RNA element on nascent viral transcripts. Binding is mediated by a 10-amino acid basic domain that is rich in arginines and lysines. Here we report the three-dimensional peptide backbone structure...

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Main Authors:	Mujeeb, A, Bishop, K, Peterlin, B M, Turck, C, Parslow, T G, James, T L, Rhoads, D M, Kaspi, C I, Levings, C S, Siedow, J N, Harata, M, Karwan, A, Wintersberger, U, Larue, L, Ohsugi, M, Hirchenhain, J, Kemler, R, Civardi, L, Xia, Y, Edwards, K J, Schnable, P S, Nikolau, B J, Maruyama, I N, Maruyama, H I, Brenner, S, Tetaud, E, Bringaud, F, Chabas, S, Barrett, M P, Baltz, T, Ishaq, M, Stoner, G L, Schmidt, K F, Kruse, M, Hatt, H, Borchelt, D R, Lee, M K, Slunt, H S, Guarnieri, M, Xu, Z S, Wong, P C, Brown, R H, Price, D L, Sisodia, S S, Cleveland, D W, Meador-Woodruff, J H, Damask, S P, Watson, S J, Huber, B E, Austin, E A, Richards, C A, Davis, S T, Good, S S, Tinsley, J M, Blake, D J, Zuellig, R A, Davies, K E, Brighty, D W, Rosenberg, M, Smiley, J A, Benkovic, S J, Whitesell, L, Mimnaugh, E G, De Costa, B, Myers, C E, Neckers, L M, Wang, X M, Yew, N, Peloquin, J G, Vande Woude, G F, Borisy, G G, Trounce, I, Neill, S, Wallace, D C, Purves, D, White, L E, Pan, Z Q, Amin, A A, Gibbs, E, Niu, H, Hurwitz, J, Carayannopoulos, L, Max, E E, Capra, J D, Fontan, E, Briend, E, Saklani-Jusforgues, H, d'Alayer, J, Vandekerckhove, J, Fauve, R M, Dixon, J F, Los, G V, Hokin, L E, Schmidt-Ott, U, González-Gaitán, M, Jäckle, H, Technau, G M, Schwarzman, A L, Gregori, L, Vitek, M P, Lyubski, S, Strittmatter, W J, Enghilde, J J, Bhasin, R, Silverman, J, Weisgraber, K H, Coyle, P K, Shang, Z, Isaac, V E, Li, H, Patel, L, Catron, K M, Curran, T, Montelione, G T, Abate, C, Näslund, J, Schierhorn, A, Hellman, U, Lannfelt, L, Roses, A D, Tjernberg, L O, Silberring, J, Gandy, S E, Winblad, B, Greengard, P, Liu, H, Wang, H, Sheng, M, Jan, L Y, Jan, Y N, Basbaum, A I, Ina, Y, Gojobori, T, Schena, M, Davis, R W, Lu, S J, Rowan, S, Bani, M R, Ben-David, Y, Bianchi, V, Borella, S, Calderazzo, F, Ferraro, P, Chieco Bianchi, L, Reichard, P, Gu, Q, Liu, Y, Cynader, M S, Joseph, P, Jaiswal, A K, Atkinson, E M, Palcic, M M, Hindsgaul, O, Long, S R, Satoh, T, Satoh, H, Iwahara, S, Hrkal, Z, Peyton, D H, Muller-Eberhard, U, Ruchaud, S, Duprez, E, Gendron, M C, Houge, G, Genieser, H G, Jastorff, B, Doskeland, S O, Lanotte, M, Ahner, B A, Price, N M, Morel, F M, Du, Y, Maslov, D A, Chang, K P, France, L L, Piatti, P G, Newman, J F, Toth, I, Gibbons, W A, Brown, F, Zhang, D, Botos, I, Gomis-Rüth, F X, Doll, R, Blood, C, Njoroge, F G, Fox, J W, Bode, W, Meyer, E F, Glerum, D M, Tzagoloff, A, Friedman, E, Bale, A E, Carson, E, Boson, W L, Nordenskjöld, M, Ritzén, M, Ferreira, P C, Jammal, A, De Marco, L, Kappler, J, White, J, Kozono, H, Clements, J, Marrack, P, de Koning, E J, Morris, E R, Hofhuis, F M, Posthuma, G, Höppener, J W, Morris, J F, Capel, P J, Clark, A, Verbeek, J S, Schrével, J, Sinou, V, Grellier, P, Frappier, F, Guénard, D, Potier, P, Packard, M G, Cahill, L, McGaugh, J L, Purpura, K P, Victor, J D, Katz, E, Probst, W C, Cropper, E C, Heierhorst, J, Hooper, S L, Jaffe, H, Vilim, F, Beushausen, S, Kupfermann, I, Weiss, K R, Hofmann, G E, Hand, S C
Formato:	Artigo
Idioma:	English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English
Publicado em:	1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.gov/pmc/articles/PMC44583/ https://ncbi.nlm.nih.gov/pubmed/8058789 https://ncbi.nlm.nih.gov/pmc/articles/PMC44584/ https://ncbi.nlm.nih.gov/pubmed/8058790 https://ncbi.nlm.nih.gov/pmc/articles/PMC44585/ https://ncbi.nlm.nih.gov/pubmed/8058791 https://ncbi.nlm.nih.gov/pmc/articles/PMC44586/ https://ncbi.nlm.nih.gov/pubmed/8058792 https://ncbi.nlm.nih.gov/pmc/articles/PMC44587/ https://ncbi.nlm.nih.gov/pubmed/8058793 https://ncbi.nlm.nih.gov/pmc/articles/PMC44588/ https://ncbi.nlm.nih.gov/pubmed/8058794 https://ncbi.nlm.nih.gov/pmc/articles/PMC44589/ https://ncbi.nlm.nih.gov/pubmed/8058795 https://ncbi.nlm.nih.gov/pmc/articles/PMC44590/ https://ncbi.nlm.nih.gov/pubmed/8058796 https://ncbi.nlm.nih.gov/pmc/articles/PMC44591/ https://ncbi.nlm.nih.gov/pubmed/7520178 https://ncbi.nlm.nih.gov/pmc/articles/PMC44592/ https://ncbi.nlm.nih.gov/pubmed/8058797 https://ncbi.nlm.nih.gov/pmc/articles/PMC44593/ https://ncbi.nlm.nih.gov/pubmed/7914704 https://ncbi.nlm.nih.gov/pmc/articles/PMC44594/ https://ncbi.nlm.nih.gov/pubmed/8058798 https://ncbi.nlm.nih.gov/pmc/articles/PMC44595/ https://ncbi.nlm.nih.gov/pubmed/8078878 https://ncbi.nlm.nih.gov/pmc/articles/PMC44596/ https://ncbi.nlm.nih.gov/pubmed/8078879 https://ncbi.nlm.nih.gov/pmc/articles/PMC44597/ https://ncbi.nlm.nih.gov/pubmed/8078880 https://ncbi.nlm.nih.gov/pmc/articles/PMC44598/ https://ncbi.nlm.nih.gov/pubmed/8078881 https://ncbi.nlm.nih.gov/pmc/articles/PMC44599/ https://ncbi.nlm.nih.gov/pubmed/8078882 https://ncbi.nlm.nih.gov/pmc/articles/PMC44600/ https://ncbi.nlm.nih.gov/pubmed/8078883 https://ncbi.nlm.nih.gov/pmc/articles/PMC44601/ https://ncbi.nlm.nih.gov/pubmed/8078884 https://ncbi.nlm.nih.gov/pmc/articles/PMC44602/ https://ncbi.nlm.nih.gov/pubmed/8078885 https://ncbi.nlm.nih.gov/pmc/articles/PMC44603/ https://ncbi.nlm.nih.gov/pubmed/8078886 https://ncbi.nlm.nih.gov/pmc/articles/PMC44604/ https://ncbi.nlm.nih.gov/pubmed/8078887 https://ncbi.nlm.nih.gov/pmc/articles/PMC44605/ https://ncbi.nlm.nih.gov/pubmed/8078888 https://ncbi.nlm.nih.gov/pmc/articles/PMC44606/ https://ncbi.nlm.nih.gov/pubmed/7915837 https://ncbi.nlm.nih.gov/pmc/articles/PMC44607/ https://ncbi.nlm.nih.gov/pubmed/8078889 https://ncbi.nlm.nih.gov/pmc/articles/PMC44608/ https://ncbi.nlm.nih.gov/pubmed/7915838 https://ncbi.nlm.nih.gov/pmc/articles/PMC44609/ https://ncbi.nlm.nih.gov/pubmed/8078890 https://ncbi.nlm.nih.gov/pmc/articles/PMC44610/ https://ncbi.nlm.nih.gov/pubmed/8078891 https://ncbi.nlm.nih.gov/pmc/articles/PMC44611/ https://ncbi.nlm.nih.gov/pubmed/8078892 https://ncbi.nlm.nih.gov/pmc/articles/PMC44612/ https://ncbi.nlm.nih.gov/pubmed/7915839 https://ncbi.nlm.nih.gov/pmc/articles/PMC44613/ https://ncbi.nlm.nih.gov/pubmed/8078893 https://ncbi.nlm.nih.gov/pmc/articles/PMC44614/ https://ncbi.nlm.nih.gov/pubmed/8078894 https://ncbi.nlm.nih.gov/pmc/articles/PMC44615/ https://ncbi.nlm.nih.gov/pubmed/8078895 https://ncbi.nlm.nih.gov/pmc/articles/PMC44616/ https://ncbi.nlm.nih.gov/pubmed/8078896 https://ncbi.nlm.nih.gov/pmc/articles/PMC44617/ https://ncbi.nlm.nih.gov/pubmed/8078897 https://ncbi.nlm.nih.gov/pmc/articles/PMC44618/ https://ncbi.nlm.nih.gov/pubmed/8078898 https://ncbi.nlm.nih.gov/pmc/articles/PMC44619/ https://ncbi.nlm.nih.gov/pubmed/7915840 https://ncbi.nlm.nih.gov/pmc/articles/PMC44620/ https://ncbi.nlm.nih.gov/pubmed/8078899 https://ncbi.nlm.nih.gov/pmc/articles/PMC44621/ https://ncbi.nlm.nih.gov/pubmed/7521530 https://ncbi.nlm.nih.gov/pmc/articles/PMC44622/ https://ncbi.nlm.nih.gov/pubmed/8078900 https://ncbi.nlm.nih.gov/pmc/articles/PMC44623/ https://ncbi.nlm.nih.gov/pubmed/8078901 https://ncbi.nlm.nih.gov/pmc/articles/PMC44624/ https://ncbi.nlm.nih.gov/pubmed/8078902 https://ncbi.nlm.nih.gov/pmc/articles/PMC44625/ https://ncbi.nlm.nih.gov/pubmed/8078903 https://ncbi.nlm.nih.gov/pmc/articles/PMC44626/ https://ncbi.nlm.nih.gov/pubmed/8078904 https://ncbi.nlm.nih.gov/pmc/articles/PMC44627/ https://ncbi.nlm.nih.gov/pubmed/8078905 https://ncbi.nlm.nih.gov/pmc/articles/PMC44628/ https://ncbi.nlm.nih.gov/pubmed/7915841 https://ncbi.nlm.nih.gov/pmc/articles/PMC44629/ https://ncbi.nlm.nih.gov/pubmed/8078906 https://ncbi.nlm.nih.gov/pmc/articles/PMC44630/ https://ncbi.nlm.nih.gov/pubmed/8078907 https://ncbi.nlm.nih.gov/pmc/articles/PMC44631/ https://ncbi.nlm.nih.gov/pubmed/8078908 https://ncbi.nlm.nih.gov/pmc/articles/PMC44632/ https://ncbi.nlm.nih.gov/pubmed/8078909
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NMR structure of a biologically active peptide containing the RNA-binding domain of human immunodeficiency virus type 1 Tat.

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